Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4595)
Related Products (4595)
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Glycitein-7-O-methyl ether
0 ImagesCat. No.: HY-W783413CAS No.: 75199-40-5Synonyms: 6-MethoxyisoformononetinGlycitein-7-O-methyl ether (6-Methoxyisoformononetin) is an isoflavone antioxidant with a IC50 of 730.53 µg/mL. Glycitein-7-O-methyl ether exhibits weak free radical scavenging activity and shows no antibacterial activity against tested bacteria and fungi. Glycitein-7-O-methyl ether can be used in antioxidant-related research.
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L-Lactic acid calcium hydrate
0 ImagesCat. No.: HY-W105639CAS No.: 865717-20-0L-Lactic acid calcium hydrate is the calcium salt of L-Lactic acid. L-Lactic acid calcium hydrate is a building block that can be used as a precursor for the production of bioplastic polymer polylactic acid.
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2'-Hydroxyacetophenone-d7
0 ImagesCat. No.: HY-W739751CAS No.: 1189865-36-8Synonyms: o-Hydroxyacetophenone-d7; o-Acetylphenol-d72'-Hydroxyacetophenone-d7 (o-Hydroxyacetophenone-d7; o-Acetylphenol-d7) is the deuterium labeled 2'-Hydroxyacetophenone (HY-Y1426). 2'-Hydroxyacetophenone is found in alcoholic beverages. 2'-Hydroxyacetophenone is present in tomato, cassia, fried beef, rum, whiskey, cocoa, coffee and black tea. 2'-Hydroxyacetophenone is a flavouring ingredient. Building block in chemical synthesis.
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Isonicotinic acid (Standard)
0 ImagesIsonicotinic acid (Standard) is the analytical standard of Isonicotinic acid (HY-I0736). This product is intended for research and analytical applications. Isonicotinic acid is a pyridine carboxylic acid compound and also a metabolite of Isoniazid (HY-B0329). Derivatives of Isonicotinic acid exhibit antiviral activity against influenza viruses.
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Methoxycarbonyl isocyanate
0 ImagesCat. No.: HY-W178414CAS No.: 5843-42-5Methoxycarbonyl isocyanate can be used for compound synthesis.
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Hydrosorbaldehyde
0 ImagesCat. No.: HY-W747972CAS No.: 4440-65-7Hydrosorbaldehyde is a green leaf volatile and also the main contributor to the fresh, grassy aroma of tea leaves. Hydrosorbaldehyde undergoes irreversible conversion to (E)-2-hexenal via (Z)-3:(E)-2-hexenal isomerase (CsHI). Hydrosorbaldehyde plays a key role in protecting plants against biotic stresses (such as pathogens and insects) and acting as a signaling chemical.
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Guaietolin
0 ImagesCat. No.: HY-W412326CAS No.: 63834-83-3Synonyms: Guaietolin (INN); Guethral; GuethuralGuaietolin is an organic synthesis intermediate. Guaietolin is a marker of hypertension with significant reduced level in plasma metabolites. Guaietolin can be used for synthesis of sulfonamide esters with carbonic anhydrase inhibitory activity. Guaietolin can be used for glaucoma and hypertension research.
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3-(5-Phenyl-1,2,4-oxadiazol-3-yl)pyridine
0 ImagesCat. No.: HY-187146CAS No.: 330656-02-53-(5-Phenyl-1,2,4-oxadiazol-3-yl) pyridine is an intermediate. 3-(5-Phenyl-1,2,4-oxadiazol-3-yl) pyridine can be used for the synthesis of positive allosteric modulators of the (α4)3 (β2)2 nicotinic acetylcholine receptor.
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1-Methylimidazole-d3-1
0 ImagesCat. No.: HY-59137S2CAS No.: 4166-68-11-Methylimidazole-d3-1 is the deuterium labeled 1-Methylimidazole. 1-Methylimidazole acts as a membrane performance regulator that promotes the formation of reverse osmosis membranes with a dense ultra-thin polyamide layer. Such membranes exhibit higher flux and salt rejection rate, while also conferring excellent pH stability to the membrane. 1-Methylimidazole can serve as a ligand for ruthenium (II) complexes to construct metal-based anticancer agents.
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ProX1-(SS)-DOTAGA
0 ImagesCat. No.: HY-185120ACAS No.: 3084147-67-8ProX1-(SS)-DOTAGA (Compound 12b) is the unbound portion of the radionuclide in the compound and can be used for targeted delivery to diseases characterized by ACP3 expression.
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H-Arg-Ser-Arg-OH
0 ImagesCat. No.: HY-134578CAS No.: 115035-42-2H-Arg-Ser-Arg-OH is a short peptide. H-Arg-Ser-Arg-OH is a motif of di-leucine and RSRR, it can be used to design larger peptides and compound.
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Antitumor agent-90
0 ImagesCat. No.: HY-153051CAS No.: 131268-74-1Antitumor agent-90 (Compound 17) has cytotoxicity against PC 14 cell and MKN 45 cell. Antitumor agent-90 can be used for cancer research.
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Fosamprenavir sodium
0 ImagesCat. No.: HY-78726ACAS No.: 226700-80-7Synonyms: Amprenavir phosphate sodium; GW 433908 sodiumFosamprenavir sodium is an orally active inhibitor targeting HIV-1 protease and is a prodrug of Amprenavir (HY-17430). Fosamprenavir sodium is hydrolyzed into Amprenavir (VX-478) by cell phosphatases in the intestinal epithelium. Amprenavir binds to the active site of HIV-1 protease, preventing the processing of viral gag and gag-pol polyprotein precursors, thereby inhibiting the formation of mature infectious virus particles and exerting anti-HIV-1 infection activity. Fosamprenavir sodium can be used for the study of human immunodeficiency virus (HIV-1) infection.
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5,8-Dimethoxyquinoxaline
0 ImagesCat. No.: HY-W1063697CAS No.: 19506-19-55,8-Dimethoxyquinoxaline is a drug intermediate that can be used in studies related to organic synthesis. The derived cyclization product of 5,8-Dimethoxyquinoxaline specifically blocks TOP1-mediated DNA cleavage reactions.
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Antiproliferative agent-48
0 ImagesCat. No.: HY-163381CAS No.: 1621594-62-4Antiproliferative agent-48 (compound PC-A1) shows selective antiproliferative activity against triple-negative breast cancer (TNBC) cells.
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Chloramphenicol succinate
0 ImagesChloramphenicol succinate is a prodrug of Chloramphenicol (HY-B0239), acting as a P2Y14R inhibitor with an IC50 of 1.585 nM. Chloramphenicol succinate serves as a competitive substrate and inhibitor of succinate dehydrogenase (SDH), which may account for its toxicity. Chloramphenicol succinate exerts a significant inhibitory effect on colitis. Chloramphenicol succinate can be used in research related to myelosuppression, gray baby syndrome, aplastic anemia, bacterial meningitis and inflammatory bowel disease.
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2,4-Dihydroxybenzaldehyde (Standard)
0 Images2,4-Dihydroxybenzaldehyde (Standard) is the analytical standard of 2,4-Dihydroxybenzaldehyde. This product is intended for research and analytical applications. 2,4-Dihydroxybenzaldehyde is an endogenous metabolite. 2,4-Dihydroxybenzaldehyde is a pharmaceutical intermediate that can be used to synthesize various Schiff base compounds. 2,4-Dihydroxybenzaldehyde exhibits significant anti angiogenic, anti-inflammatory, and analgesic activities. 2,4-Dihydroxybenzaldehyde reduces the production of NO and ROS by inhibiting the expression of iNOS and COX-2. 2,4-Dihydroxybenzaldehyde is commonly used in the study of inflammatory conditions.
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Anticancer agent 346
0 ImagesCat. No.: HY-184941CAS No.: 3099596-05-8Anticancer agent 346 is an anticancer agent. Anticancer agent 346 exhibits anticancer activity against breast cancer.
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Acetylpyrazine (Standard)
0 ImagesCat. No.: HY-W007692RCAS No.: 22047-25-2Synonyms: 2-Acetylpyrazine (Standard)Acetylpyrazine (2-Acetylpyrazine) (Standard) is the analytical standard of Acetylpyrazine. This product is intended for research and analytical applications. Acetylpyrazine is a ketone compound and can be used for drug synthesis.
